ea0056p993 | Clinical case reports - Thyroid/Others | ECE2018
Bedoya Vanessa
, Miguel Osorio Luis
, Santrich Melanie
, Castano Orlando
, Eugenia Casanova Maria
, Velasco Margarita
, Abreu Alin
Introduction: Rituximab is indicated in patients with active rheumatoid arthritis (RA), which through the Fab domain, binds to the CD20 antigen on the surface of B lymphocytes, generating lysis of B cells, present in the thyroid, by cytotoxicity dependent on complement, as a result of the binding of C1q, mediated by the Fc domain, destroying the thyroid follicles, by infiltration of inflammatory cells (1) (2).Objective: Describe the characteristics of pa...